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Predictive Power

Below, we present the prediction performance on an 'out-of-sample' test set of the European ancestry siblings in the UK Biobank. These individuals were completely excluded from model development, providing us an opportunity to assess the actual predictive power of our disease forecaster.

Sibling pairs offer a way to evaluate how well our predictors capture direct biological effects. We demonstrate our ability to predict, from the information gathered at the doctor visit + genetics, which sibling will be diagnosed within a disease within 10 years.